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In a transected rat sciatic nerve model (Gjurasin et al., 2010, published in Regulatory Peptides), BPC-157 promoted functional nerve reconnection and accelerated axonal sprouting, with treated animals recovering motor function significantly faster than controls
DOI:10.1186/s13018-019-1242-6 3.T.Huang,K.Zhang,L.Sun,X.Xue,C.Zhang,Z.Shu,N.Mu,J.Gu,W.Zhang,Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro
The lack of robust human clinical trials
Their approach: aspirate the hemarthrosis within 1-2 weeks of injury removing the inflammatory environment from the joint then deliver anakinra (IL-1 receptor antagonist) directly into the knee during that narrow biological window